Advanced Biotic

100% clean formula.

Suitable for vegetarians and vegans. All Ethical Nutrition products are free from animal-based ingredients and by-products. Registered with the vegan society.

Free-from: GMOs, Magnesium Stearate, Gelatin, Palm Oil/Palm Oil Derivatives, Maltodextrin, Bulking Agents, Titanium Dioxide, Sugar.

No Allergen-Containing Ingredients: This product is formulated without any ingredients from the top 14 allergens, including wheat, milk, nuts, soy, and shellfish.

Additive-free: We don't use any nasty additives and where required we use gluten-free rice extract to help us to blend together ingredients and ensure they are accurately dosed.

Probiotic bacteria including the ones we use in Advanced Biotic have a wide range of health benefits. They’ve been shown to:

• Optimise digestion and nutrient absorption: Lactic acid producing bacteria like Lactobacillus Acidophilus can support the breakdown and absorption of nutrients and help manage lactose intolerance (the inability to digest the milk sugar, lactose) [1].
• Support immune function: Did you know around 70% of your immune system resides in your gut? Gut bacteria help regulate immune function and modulate inflammatory pathways to make sure the immune system doesn’t overreact or underreact [2]. They also maintain a healthy gut wall to prevent potential pathogens being absorbed into the blood stream [2]. 
• Mental wellbeing: Gut bacteria are the main source of short-chain fatty acids (SCFAs) which modulate brain behaviour and support mental health. Your gut bugs also metabolise various neurotransmitters including GABA (gamma amino butyric acid) and serotonin that are thought to reduce anxiety and depression [3]. 
• Weight management: Weight balance is influenced by numerous factors including the health and diversity of your gut microbiome. Research shows that probiotics (and prebiotics) may alter the release of hormones and other chemical messengers and modulate the triggers of food consumption that lead to weight gain [4]. 
• Support the balance and diversity of your gut flora: Microbiome health is not just about supplementing with different strains of bacteria but about creating the right kind of environment for all sorts of beneficial microbes to flourish. This allows friendly strains to thrive and keeps potentially harmful ones in check [5]. This is helpful for managing conditions associated with an imbalance in gut bacteria (known as dysbiosis). These include Irritable Bowel Syndrome, candida overgrowth, and inflammatory bowel conditions. 

Probiotics may be helpful if you:

• Have recently taken or are taking a course of antibiotics.
• Are managing digestive issues like Irritable Bowel Syndrome or an inflammatory gut condition.
• Want to optimise your immune system.
• Want to support your mental health.
• Are looking to lose weight.

Probiotics are recognised as being generally safe to take. However they can be contraindicated for people with severely compromised immune systems and those taking immunosuppressant medications.

No, they are not. Different probiotic blends contain different combinations of bacteria and the various strains work in different parts of your gut. 

Some probiotics contain a large number of strains but more doesn’t necessarily mean better. When it comes to probiotics it’s about quality not just quantity [6].

We chose the 4 strains in Advanced Biotic because they work synergistically to support gut health and have a range of proven health benefits.

Comparing a probiotic with a prebiotic is like comparing apples and oranges; they’re both fruit but they don’t look or taste the same. Pre- and probiotics both work in the gut but they do different things.

A probiotic supplement contains strains of beneficial bacteria whereas a prebiotic supplement is a substance that feeds and nourishes the friendly bacteria already in living in your gut. 

It is fine to take either of these products individually or in combination. For complete gut support, check out our Gut Health Bundle that contains Advanced Biotic along with Digestive Enzymes and Prebiotic Restore.

There’s a constant channel of communication between your gut and brain known as the gut-brain connection (or the gut-brain axis). 

The “talking” is done by nerve signals travelling up and down the vagus nerve (a large nerve that runs from the brain down through the digestive tract), and chemical messengers produced by microbes in the gut. It’s a complex network of messages that influences everything from anxiety and mood balance to cognition and pain [7]. 

Probiotics like our Advanced Biotic help maintain a healthy and diverse gut microbiome and optimise the gut-brain connection for overall health and wellbeing.

When taken as directed, our Advanced Biotic is well tolerated. However, do bear in mind that live bacteria can temporarily disturb the balance of microbes already present in your gut. This can sometimes cause some short-lived wind, bloating, and changes in bowel habits. If this is uncomfortable, we recommend you reduce the dosage to 1 capsule per day until the symptoms have eased.

1. Liu, Y., Nawazish, H., Farid, M.S., Abdul Qadoos, K., Habiba, U.E., Muzamil, M., Tanveer, M., Sienkiewicz, M., Lichota, A., Łopusiewicz, Ł. 2024. Health-Promoting Effects of Lactobacillus acidophilus and Its Technological Applications in Fermented Food Products and Beverages. Fermentation. 10(8):380. https://doi.org/10.3390/fermentation10080380
2. Belkaid, Y., & Hand, T. W. 2014. Role of the microbiota in immunity and inflammation. Cell, 157(1), 121–141 doi.org/10.1016/j.cell.2014.03.011
3. Merkouris, E., Mavroudi, T., Miliotas, D., Tsiptsios, D., Serdari, A., Christidi, F., Doskas, T.K., Mueller, C., Tsamakis, K. 2024. Probiotics' Effects in the Treatment of Anxiety and Depression: A Comprehensive Review of 2014-2023 Clinical Trials. Microorganisms. Feb 19;12(2):411. doi:10.3390/microorganisms12020411.
4. Noor, J., Chaudhry, A., Batool, S., Noor, R., Fatima, G. 2023. Exploring the Impact of the Gut Microbiome on Obesity and Weight Loss: A Review Article. Cureus. Jun 25;15(6):e40948. doi: 10.7759/cureus.40948. 
5. Ilhan, Z.E., Marcus, A.K., Kang, D.W., Rittmann, B.E., Krajmalnik-Brown, R. 2017. pH-Mediated Microbial and Metabolic Interactions in Fecal Enrichment Cultures. mSphere. May 3;2(3):e00047-17. doi: 10.1128/mSphere.00047-17. PMID: 28497116; PMCID: PMC5415631.
6. Hill, C., Guarner, F., Reid, G., Gibson, G. R., Merenstein, D. J., Pot, B., Morelli, L., Canani, R. B., Flint, H. J., Salminen, S., Calder, P. C., & Sanders, M. E. 2014. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature reviews. Gastroenterology & Hepatology 11(8), 506–514 doi.org/10.1038/nrgastro.2014.66

Cryan, J. F., & Dinan, T. G. 2012. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nature reviews. Neuroscience 13(10), 701–712. doi.org/10.1038/nrn3346