Prebiotic Restore

Prebiotic Restore

2 capsules provide:

Ingredients: Actazin® Kiwi Fruit Powder, Livaux® Gold Kiwi Fruit Powder, Capsule Shell (Vegetable Cellulose).

100% clean formula.

Suitable for vegetarians and vegans. All Ethical Nutrition products are free from animal-based ingredients and by-products. Registered with the vegan society. 

Free-from: GMOs, Magnesium Stearate, Gelatin, Palm Oil/Palm Oil Derivatives, Maltodextrin, Bulking Agents, Titanium Dioxide, Sugar. 

Allergen-free: totally free from gluten and allergen containing ingredients.

Additive-free: We don't use any nasty additives and where required we use gluten-free rice extract to help us to blend together ingredients and ensure they are accurately dosed.

By feeding the good bacteria inside your gut, prebiotics help gut bugs produce short chain fatty acids and other metabolites. These fatty acids help to:
- Regulate the pH level inside the gut. A lower, more acidic pH keeps less-favourable microbes in check [1].
- Feed the cells lining the gut. A healthy gut barrier prevents the development of increased intestinal permeability AKA “leaky gut”.
- Optimise immune defences and enhance disease resistance [1].
- Influence fat, glucose, and cholesterol metabolism [2].
- Communicate with the brain to influence depression and mental health [3].
In addition, the prebiotic fibres themselves have benefits too.

They have been shown to [4]:

- Promote healthy bowel movements.
- Help regulate blood sugar balance and energy levels.
- Reduce cravings by helping you feel fuller for longer.

Prebiotic Restore is a cutting-edge blend of:

- Actazin® the patented form of actinidin, a natural digestive enzyme derived from green kiwifruit. Actazin® is proven to enhance protein digestion, ease bloating and uncomfortable fullness, and improve bowel regularity [5].

- Livaux® a unique prebiotic found in the golden kiwi, proven to support levels of the probiotic bacteria Faecalibacterium Prausnitzii (F. Prausnitzii). F. Prausnitzii produces butyrate, a short chain fatty acid that acts as fuel for gut cells and as an important signalling molecule between the gut and the brain.Each daily dosage (2 capsules) provides 600mg of Actazin® and 600mg Livaux® – the clinically effective doses of each active ingredient.

No, they are not the same thing.

Probiotics are beneficial strains of bacteria and yeast that are good for our health.The name “probiotic” translates as “pro-life” (“bio” meaning “life”).

You can find probiotics in foods like natural live yoghurt, kefir, and kimchi, or in supplements like our Advanced Biotic.

Prebiotics feed the probiotics. They’re like compost in a garden, providing nourishment to the plants. Without prebiotics, the probiotic bacteria struggle to thrive.

Low numbers of probiotics mean that more harmful strains of bacteria grow instead.

We need both probiotics and prebiotics for good gut health. Prebiotics feed the probiotics, and the probiotics rely on this nourishment to survive and thrive.

Yes, prebiotics and probiotics work in synergy with one another to support gut health. The prebiotic provides food for the probiotic, helping it flourish and grow. Our Digestive Bundle contains prebiotics, probiotics, and digestive enzymes for complete gut support.

Like all types of fibre, prebiotics need to be taken with plenty of water. The fibre soaks up the water to help form poops that are soft and easy-to-pass. Not drinking enough water will make constipation worse whether you use a prebiotic or not.

No, Prebiotic Restore does not need to be refrigerated and can be safely stored at room temperature.

When taken as directed Prebiotic Restore is generally well tolerated. Those with a sensitive digestion may experience a mild upset stomach, wind, or bloating but this should settle down in a few days.Do not use this product if you have a latex allergy. Kiwifruits contain similar proteins to latex and can potentially trigger an allergic response.

Actazin® and Livaux®, the active ingredients in Prebiotic Restore are backed by clinical trials demonstrating their effectiveness.

Actazin®

In 2010, researchers discovered that actinidin, the kiwi-derived digestive enzyme in Actazin®, could enhance the digestion of certain proteins from soy, dairy, and beef [6]. Later studies highlighted a similar enhancing effect on gluten digestion [7]. 

Further research found that actinidin can reduce bloating and gastric discomfort [8] and increase the rate at which amino acids (the small building blocks of protein) are absorbed into the bloodstream [9].

Alongside actinidin, Actazin® contains kiwifruit fibres that have a unique ability to retain water [10]. The fibre swells into a gel which softens and bulks out poop, making it easier to pass through the bowel. 

In a randomized, placebo-controlled, double-blinded study using 600mg of Actazin® (the amount we use in Prebiotic restore), participants experienced clinically significant improvements in stool formation and bowel habits. Unlike other forms of laxative, Actazin® was safe and well tolerated [11].

Livaux®

Livaux® is the unique prebiotic found in golden kiwifruit. In a 4-week randomised controlled trial, Livaux® significantly increased levels of the friendly gut bacteria Faecalibacterium prausnitzii (F. prausnitzii) from 3·4 to 7·0 % in functionally constipated participants [12]. 

F. prausnitzii is one of the crucial butyrate producing bacteria in a healthy gut microbiome. Butyrate is a short chain fatty acid that plays a key role in managing inflammation, gut health, and gut-brain communications. Low levels of F. prausnitzii are associated with an imbalanced microbiome and the development of inflammatory conditions like colitis, depression, and dermatitis [13].

It’s important to note that the trial achieved these results using 600mg of Livaux® - the same amount we use in Prebiotic Restore. When you choose Prebiotic Restore you are guaranteed to receive the levels of Actazin® and Livaux® that are clinically proven to support protein digestion, bowel regularity, and overall digestive wellbeing.

1. Davani-Davari, D., Negahdaripour, M., Karimzadeh, I., Seifan, M., Mohkam, M., Masoumi, S.J., Berenjian, A., Ghasemi, Y. (2019). Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods, 8(3), 92. PMID: 30857316; PMCID: PMC6463098.
2. Galisteo, M., Duarte, J., Zarzuelo, A. (2008). Effects of dietary fibers on disturbances clustered in the metabolic syndrome. Journal of Nutritional Biochemistry, Feb;19(2):71-84.
3. Cheng, J., Hu, H., Ju, Y., Liu, J., Wang, M., Liu, B., Zhang, Y. (2024). Gut microbiota-derived short-chain fatty acids and depression: deep insight into biological mechanisms and potential applications. General Psychiatry, Feb 19;37(1)
4. Marlett, J.A., McBurney, M.I., Slavin, J.L. (2002). American Dietetic Association. Position of the American Dietetic Association: health implications of dietary fiber. Journal of the American Dietetic Association, Jul;102(7):993-1000.
5. Actazin, n.d. Improve bowel regularity and digestion and bloat less with Actazin® [online]. Available at: https://actazin.com/science-story/
6. Kaur, L., Rutherfurd, S. M., Moughan, P. J., Drummond, L., & Boland, M. J. 2010. Actinidin enhances gastric protein digestion as assessed using an in vitro gastric digestion model. Journal of Agricultural and Food Chemistry, 58(8), 5068–5073. https://doi.org/10.1021/jf903332a
7. Jayawardana, I. A., Boland, M. J., Loo, T. S., McNabb, W. C., & Montoya, C. A. 2022. Actinidin reduces gluten-derived immunogenic peptides reaching the small intestine in an in vitro semi-dynamic gastrointestinal tract digestion model. Food Research International (Ottawa, Ont.), 159, 111560. doi.org/10.1016/j.foodres.2022.111560
8. Wallace, A., Eady, S., Drummond, L., Hedderley, D., Ansell, J., & Gearry, R. 2017. A Pilot Randomized Cross-Over Trial to Examine the Effect of Kiwifruit on Satiety and Measures of Gastric Comfort in Healthy Adult Males. Nutrients, 9(7), 639. https://doi.org/10.3390/nu9070639
9. Park, S., Church, D. D., Starck, C., Schutzler, S. E., Azhar, G., Kim, I. Y., Ferrando, A. A., Moughan, P. J., & Wolfe, R. R. 2021. The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism. European Journal of Nutrition, 60(2), 1141–1148. https://doi.org/10.1007/s00394-020-02363-5
10. Sims, I. M., & Monro, J. A. 2013. Fiber: composition, structures, and functional properties. Advances in Food and Nutrition Research, 68, 81–99. https://doi.org/10.1016/B978-0-12-394294-4.00005-5
11. Graham, E., McKeen, S., Lewis, E. D., Evans, M., Li, Z., Henning, S. M., Jopson, N., Gu, J., & Rosendale, D. 2024. Actazin® green kiwifruit powder consumption at 600 mg per day for 28 days improves stool form and relieves occasional constipation in healthy individuals: A randomized controlled trial. Bioactive Carbohydrates and Dietary Fibre, 32, 100436. https://doi.org/10.1016/j.bcdf.2024.100436
12. Blatchford, P., Stoklosinski, H., Eady, S., Wallace, A., Butts, C., Gearry, R., Gibson, G., & Ansell, J. 2017. Consumption of kiwifruit capsules increases Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial. Journal of Nutritional Science, 6, e52. https://doi.org/10.1017/jns.2017.52
13. Martín, R., Rios-Covian, D., Huillet, E., Auger, S., Khazaal, S., Bermúdez-Humarán, L.G., Sokol, H., Chatel, J.M., Langella, P. 2023. Faecalibacterium: a bacterial genus with promising human health applications. FEMS Microbiology Reviews. Jul 5;47(4):fuad039. doi: 10.1093/femsre/fuad039. PMID: 37451743; PMCID: PMC10410495.